This study aimed to evaluate the prognostic value of the serum lactate-to-albumin (L/A) ratio for sepsis and compare its performance with the Sequential Organ Failure Assessment (SOFA) score in predicting clinical outcomes.<h4>Materials and methods</h4>This prospective observational study was conducted at a tertiary care centre from June 2024 to December 2025 and included 90 adult patients diagnosed with sepsis. This evidence concerns the gene ALB and Sepsis.