However, its role in predicting AF recurrence after catheter ablation (CA) remains unexplored.<h4>Objective</h4>This study aimed to evaluate the predictive value of TNFSF14 for AF recurrence post-ablation.<h4>Methods</h4>A total of 263 AF patients undergoing CA were enrolled and stratified into two groups based on AF recurrence during a mean follow-up of 363 ± 144 days. This evidence concerns the gene TNFSF14 and atrial fibrillation.