Endometrial measurements negatively correlated with AMH and FSH concentrations, and positively with estradiol, prolactin, 17-hydroxyprogesterone, fasting insulin, and insulin resistance.<h4>Conclusions</h4>A significant association was identified between menstrual cycle regularity and uterine morphology, influenced by hormonal, metabolic, and clinical factors. The gene discussed is PRL; the disease is Insulin resistance.