IGHE and Pruritus: Elevated total serum immunoglobulin E (IgE) levels have been reported in scabies; however, their association with persistent pruritus following treatment remains unclear.<h4>Methods</h4>This observational analytical study with follow-up assessment included 66 subjects (30 scabies, 36 non-scabies) recruited from Sardjito General Hospital, affiliated hospitals (Sleman Regional General Hospital), and boarding schools in Yogyakarta, Indonesia.