For experimental validation, key inflammatory cytokines and proteins (Interleukin-6 (IL-6), Interleukin-1α (IL-1α), Interleukin-1β (IL-1β), Matrix Metallopeptidase 9 (MMP9), Chemokine Ligand 2 (CCL2), and Intercellular Adhesion Molecule 1 (ICAM1)) were measured using Enzyme-Linked Immunosorbent Assay (ELISA), immunohistochemistry (IHC), and immunofluorescence.<h4>Results</h4>Histopathological analysis showed that HQHF significantly alleviated liver steatosis and inflammatory cell infiltration. Here, CCL2 is linked to fatty liver disease.