The RM1 (Ras/Myc) mouse model is a valuable tool for studying interactions between prostate tumors and the bone marrow immune landscape.<h4>Methods</h4>Single-cell RNA sequencing was employed to investigate how CCR6 deficiency affects immune cell comsmunication in bone marrow from RM1 prostate cancer bone metastasis. The gene discussed is CCR6; the disease is prostate cancer.