TCF21 and preeclampsia: RESULTS: Compared with controls, women with preeclampsia had higher sFlt-1 (11.4-fold; p < 0.001), a higher sFlt-1/PlGF ratio (40.6-fold; p < 0.001), and higher urinary TCF21 (1.7-fold; p < 0.001), with lower PlGF (− 68%; p < 0.001).