SERPINA6 and septic shock: TS3 Asn347 CBG glycoform concentration less than 27.9 nmol/L was also associated with increased 28-day mortality (adjusted HR 2.2; 95% CI, 1.1-4.4; <i>P</i> = .023), which was not the case with lowest tertile of total CBG concentration (<200 nmol/L).<h4>Conclusion</h4>Deficiency of the Asn347 TS3 CBG glycoform is associated with ICU and 28-day mortality in septic shock.