Kaplan-Meier analysis revealed that the 12 months RFS rate after radical hysterectomy was approximately 68.29% in cervical cancer patients with positive CDK15 expression, which was lower than the 89.74% in patients with negative CDK15 expression(Log-rank P=0.019).<h4>Conclusion</h4>CDK15 and L1CAM are highly expressed in cervical cancer tissues. The gene discussed is L1CAM; the disease is cervical cancer.