Antigen-specific CD8<sup>+</sup> T cell populations and characteristics were investigated to examine the effect of liposome formulations.<h4>Results</h4>GM3 was readily incorporated into immunogenic liposomes and did not interfere with the particle formation with a recently discovered murine renal carcinoma MHC-I neoepitope, Nes2LR. This evidence concerns the gene CD8A and renal carcinoma.