Although traumatic brain injury (TBI) induces marked alterations in meningeal immune cells, their role in regulating meningeal lymphatic function under physiological and pathological conditions remains unclear.<h4>Methods</h4>Single-cell RNA sequencing, confocal microscopy, and flow cytometry were performed to identify a distinct population of meningeal fibroblasts that secrete VEGF-C and to investigate alterations in this population following TBI. The gene discussed is VEGFC; the disease is brain injury.