Flow cytometry and western blot revealed that SSG can increase the proportion of CD8<sup>+</sup> central memory T cells, reduce the proportion of CD8<sup>+</sup> effector memory T cells, reduce the proportion of CD4<sup>+</sup>CD25<sup>+</sup>Foxp3<sup>+</sup> Treg cells, and play a role in regulating the tumor microenvironment. The gene discussed is FOXP3; the disease is neoplasm.