SULT2A1 and type 2 diabetes mellitus: In female patients, an inverse relationship between TT and DR was attenuated and rendered nonsignificant after full multivariable adjustment, and neither DHEAS nor ASD showed a statistically significant association with DR risk.<h4>Conclusions</h4>Lower serum DHEAS concentrations are independently linked with elevated DR risk in males with T2DM, suggesting a potential role for DHEAS in the pathophysiology of DR in males.