Multivariable regression analysis identified older age (AOR 1.04, 95% CI 1.02-1.07), diabetes mellitus (AOR 1.89, 95% CI 1.20-2.98), prolonged dialysis duration (AOR 1.28, 95% CI 1.12-1.46), elevated CRP (AOR 1.75, 95% CI 1.08-2.84), and moderate-to-severe hepatic dysfunction (AOR 2.14, 95% CI 1.31-3.48) as independent predictors of CAD, while albumin demonstrated a protective association (AOR 0.72, 95% CI 0.54-0.96).<h4>Conclusion</h4>CAD is highly prevalent among ESRD patients undergoing maintenance dialysis with concurrent hepatic dysfunction. The gene discussed is ALB; the disease is diabetes mellitus.