NAMPT and Cerebral ischemia: <h4>Objective</h4>This study investigated the protective effect of Salidroside (SAL) against cerebral ischemia-reperfusion (I/R) injury and its role in regulating nicotinamide phosphoribosyltransferase (NAMPT)-mediated neuroinflammation and damage.<h4>Methods</h4><i>In vivo</i>, a middle cerebral artery occlusion/reperfusion (MCAO/R) model was established in male SD rats.