NPPB and endocarditis: In subgroup analyses, mortality was associated with BNP and NYHA in valvular disease; age, BMI, and surgical urgency in coronary artery disease; BNP, BMI, CPB, and minimally invasive surgery (MIS) in endocarditis; and CPB time in aortic pathology.<h4>Conclusions</h4>In-hospital mortality in cardiac surgery at HSJD decreased compared to the previous five-year period.