MAP3K14 and breast cancer: Early identification of subclinical myocardial injury is crucial to prevent progression to irreversible dysfunction.<h4>Objectives</h4>To evaluate whether a multimodal surveillance strategy integrating left ventricular global longitudinal strain (LVGLS), left atrial reservoir strain (LASr), and high-sensitivity troponin I (hs-TnI) can predict early anthracycline-induced cardiotoxicity.<h4>Methods</h4>This retrospective cohort study included 50 female breast cancer patients (mean age 49.3 ± 8.5 years) treated between January 2022 and December 2024.