LC3B expression was also assessed in paraffin-embedded human uterine samples from women with histologically confirmed adenomyosis and from controls without uterine pathology.<h4>Results</h4>At one month, a restricted set of autophagy/apoptosis-related transcripts (<i>Akt1, Mapk1, Nfkb1, Cxcr4, Bax, Bcl2, Bcl2l1 and Ulk2</i>) was modulated, and LC3B protein levels were decreased, coinciding with early myometrial disorganization and stromal invasion. This evidence concerns the gene MAPK1 and adenomyosis.