Gut microbe &lt;i&gt;Terrisporobacter&lt;/i&gt; promotes papillary thyroid carcinoma progression by upregulating the &lt;i&gt;NTRK1&lt;/i&gt; oncogene and fostering an immunosuppressive tumor microenvironment. The gene discussed is NTRK1; the disease is thyroid gland papillary carcinoma.