CYBC1 and chronic granulomatous disease: X-linked variants occur in the <i>CYBB</i> gene, whereas autosomal recessive variants are found in the <i>CYBA, NCF1, NCF2, NCF4</i>, and <i>CYBC1</i> genes.<h4>Results</h4>This study analyzed data from 14 CGD patients across 12 families using functional, molecular, and genetic approaches.