In mouse models, for example, Vγ1<sup>+</sup> and Vγ7<sup>+</sup> IELs mediate potent antitumor immunity, whereas Vγ4<sup>+</sup> and Vγ6<sup>+</sup> LPLs can acquire IL-17-dependent pro-tumor functions. This evidence concerns the gene IL17A and neoplasm.