Alternative splicing was pervasive, with recurrent high-magnitude events at cancer-relevant loci including GJA1 (SE), NF2 (A3/A5), LIN37 (A5), ECT2 (A3/A5), BCL2L11 (A3), UQCRH (A5), CSE1L (A3), BROX (A3), and multiple ZNFs. Here, CSE1L is linked to cancer.