ERBB4 and non-small cell lung carcinoma: Thus, the oncogenic functions of circGCLM, including the promotion of DDP resistance and other malignant phenotypes, were mediated through the miR-505-3p/ERBB4 axis.<h4>Conclusions</h4>In summary, our findings established that circGCLM contributed to DDP resistance in NSCLC, at least in part, by sponging miR-505-3p to derepress ERBB4, highlighting a potential therapeutic target for overcoming chemoresistance.