BIRC5 and bladder transitional cell carcinoma: Finally, we confirmed that BIRC5 exhibited high expression levels in BLCA and was involved in modulating the malignant proliferation, migratory activity, and invasive behavior of BLCA cells in vitro.<h4>Conclusion</h4>The investigative group validated the oncogenic activity of BIRC5, a gene correlated with the tumor-immune cycle.