MT-RNR1 and polycystic ovary syndrome: All participants had the wild-type (A/A) genotype for the m.1382A>C polymorphism.<h4>Conclusion</h4><h4>Results</h4>indicate that the MOTS-c gene (m.1382A>C) polymorphism shows no significant association with PCOS, and serum MOTS-c levels are comparable between individuals with PCOS and healthy controls, suggesting that MOTS-c may have a minor involvement in the pathophysiology of PCOS.