According to the model, a Nomogram was created to visualize the risk of LRTI, and another 66 patients from March 2023 to May 2023 were recruited to validate the prediction model.<h4>Results</h4>The univariate analysis showed that preoperative head and neck surgery history, WBC, PCT, CRP, tumor T stage, tumor N stage, and the SSAV changes had significantly positive relationships with postoperative LRTI. The gene discussed is CRP; the disease is neoplasm.