CD8A and neoplasm: Subcutaneous tumor models were used to determine the effects of <i>Atad2</i> deletion on LA accumulation, CD8<sup>+</sup> T cell infiltration, tumor growth, and response to anti-PD-1 therapy.<h4>Results</h4>ATAD2 was significantly upregulated in LUAD and correlated with poor survival and decreased CD8<sup>+</sup> T cell infiltration.