STAG2 and myelodysplastic syndrome: Protein-protein interaction (PPI) networks were conducted using the STRING database, and functional enrichment analyses were performed using Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), Reactome, and Transcription factors PPIs (TFPPI) databases.<h4>Results</h4>Reduced STAG2 expression was detected in 67% (65/97) of MDS cases, with 51.5% exhibiting intermediate and 15% low expression.