In logistic regression analysis, A/L emerged as the only independent predictor, with each unit increase reducing the odds of MetS by 8.3%, whereas BMI was a consistent predictor across age groups.<h4>Conclusion</h4>Galectin-1, adiponectin, and the A/L ratio are associated with MetS, with the A/L serving as a robust independent predictor. The gene discussed is ADIPOQ; the disease is metabolic syndrome.