We also used Western blot and immunofluorescence staining to evaluate the effects of epithelial-mesenchymal transition on the human prostate cancer cells in response to the B cell cytokines.<h4>Results</h4>Our findings showed an increase in migration of human prostate cancer cells in response to co-cultured B cells as well as the identified B cell cytokines: IL-6, IL-10, and CCL5. The gene discussed is CCL5; the disease is Familial prostate cancer.