RARRES2 and COVID-19: In contrast, baseline chemerin levels were significantly higher in COVID-19 patients than in controls (234.3 [164.9-269.9] vs. 144.7 [98.0-213.2] ng/mL; <i>p</i> = 0.001) and remained elevated at Day 7 (243.7 [171.0-376.7] ng/mL, <i>p</i> = 0.001 vs. controls), with a non-significant trend toward an increase over time (<i>Δ</i> chemerin +42.6 ng/mL; <i>p</i> = 0.071).<h4>Conclusion</h4>In this cohort of hospitalized but predominantly non-critically ill patients, COVID-19 was associated with sustained elevation of circulating chemerin but not with alterations in omentin levels.