TNF and rheumatoid arthritis: <h4>Purpose</h4>This real-world study compared the effects of JAK inhibitors (JAKi) versus TNF inhibitors (TNFi) on bone health and survival in rheumatoid arthritis (RA) patients.<h4>Methods</h4>We conducted a retrospective cohort study using the collaborative electronic health records (EHR) database network (2016-2024).