The albumin level in patients with DN with the A/A genotype was the highest, whereas it was the lowest in patients with the G/G genotype of <i>TGF-β1</i> rs1800470.<h4>Conclusions</h4><i>TGF-β1</i> rs1800470 and albuminuria are significantly associated with DN. Here, ALB is linked to liver dysplastic nodule.