Ki-67 LI and TERT mutation exert relatively independent effects on ITSS grade and allow reverse inference of their status from SWI, whereas IDH1 mutation influences ITSS grade indirectly via Ki-67 LI.<h4>Relevance statement</h4>This study establishes a connection between preoperative imaging and molecular glioma pathology via 7-T SWI. Here, MKI67 is linked to central nervous system cancer.