GZMK and tuberculosis: This subset was inducible by in vitro <i>Mtb</i> stimulation of healthy PBMCs.<h4>Discussion</h4>These findings reveal granzyme remodeling and altered distribution of GZMK<sup>+</sup>CD56<sup>bright</sup> NK cells associated with CCR5<sup>bright</sup> expression in TB, suggesting their potential involvement in tissue-specific NK responses.