While transient receptor potential (TRP) ion channels are expressed in the dorsal root ganglia (DRG) and are implicated in osteoarthritis pain (e.g., through Artemin/GFRA3-mediated changes to TRPV1 and TRPA1 electrical properties), there is currently only indirect evidence of TRP ion channel expression in the feline DRG. The gene discussed is GFRA3; the disease is osteoarthritis.