Finally, we established a neonatal rat model of hyperoxia-induced lung injury mimicking BPD and intervened with GB.<h4>Results</h4>We observed early activation of platelets and neutrophils in the peripheral blood of BPD patients, with elevated plasma levels of PAF and myeloperoxidase-DNA (MPO-DNA). The gene discussed is MPO; the disease is bronchopulmonary dysplasia.