This study describes disease-related symptoms and healthcare resource utilization (HRU) in this population.<h4>Methods</h4>A retrospective review of adult patients with claudin 18.2-positive (CLDN18.2+), human epidermal growth factor receptor 2-negative (HER2-), LA unresectable or mG/GEJ adenocarcinoma was performed. The gene discussed is ERBB2; the disease is gastroesophageal junction adenocarcinoma.