Reviewing the literature, among the 62 reported cases in China, 44 were typical reninoma, 16 were atypical reninoma (patients presented only with hypertension and normal serum potassium levels), and 2 were non-functional reninomas.<h4>Conclusion</h4>Young women presenting with high renin and aldosterone, with or without hypokalemia, should raise suspicion for reninoma. This evidence concerns the gene REN and hypertensive disorder.