GDF15 and Sepsis: Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine that is elevated in critical illness; however, its clinical associations and immune cell-specific context in sepsis remain incompletely characterized.<h4>Methods</h4>In this prospective observational exploratory study, serum GDF-15 concentrations were measured by enzyme-linked immunosorbent assay in a small cohort of adult patients with sepsis (n = 19) and healthy controls (n = 23).