Utilizing corneal stromal tissues from patients who undergoing Small Incision Lenticule Extraction (SMILE) surgery, the expression levels of ATF3, GRIN2B, and GSTM3 were found to be significantly lower in the high myopia group (≤ -6.00 D) compared to the low myopia group (≥ -3.00 D and < 0 D). Here, ATF3 is linked to myopia.