Additionally, the combinatorial analysis of galectins with classic markers CA15-3 and CRP showed that combinations with galectin-1, -3 and -7 may improve the diagnostic performance of single classical markers in discriminating BC from benign lesions.<h4>Conclusions</h4>The results of the study may confirm the importance of galectins in the immune response and the development of inflammatory reactions in BC. The gene discussed is LGALS1; the disease is breast cancer.