Additionally, the combinatorial analysis of galectins with classic markers CA15-3 and CRP showed that combinations with galectin-1, -3 and -7 may improve the diagnostic performance of single classical markers in discriminating BC from benign lesions.<h4>Conclusions</h4>The results of the study may confirm the importance of galectins in the immune response and the development of inflammatory reactions in BC. This evidence concerns the gene CRP and breast cancer.