Clinical activity, biochemical markers (C-reactive protein, fecal calprotectin), nutritional biomarkers (albumin, prealbumin, micronutrients), body mass index (BMI), malnutrition risk (self-administered Malnutrition Universal Screening Tool, MUST), and diet quality (PREDIMED and an expanded "Nootric score") were assessed at baseline, 12 weeks, and 24 weeks. This evidence concerns the gene CRP and nutritional deficiency disease.