SLC20A2 and primary biliary cholangitis: The patient had a positive AlzOn result, indicating an increased tendency for amyloid oligomerization and suggesting a potential indirect link between SLC20A2 and amyloid-beta pathways.<h4>Conclusions</h4>A novel frameshift mutation, Asn384Lysfs*30, in the <i>SLC20A2</i> gene was identified in a patient with Primary Brain Calcification (PBC).