Our previous studies confirmed that composite probiotics derived from fermented camel milk (CPCM), containing <i>Lactobacillus harbinensis</i> and 13 other strains, can ameliorate glucose and lipid metabolism in T2DM mice by reshaping bile acid profiles, and its effect may be associated with the PPARγ-LXRα-NPC1L1 signaling pathway. The gene discussed is PPARG; the disease is type 2 diabetes mellitus.