PPARG and metabolic dysfunction-associated steatohepatitis: Furthermore, the HFC+Fr diet increased the expression of hepatocyte peroxisome proliferator-activated receptor γ (<i>Pparg</i>), but the knockout of <i>Pparg</i> in hepatocytes (<i>Pparg</i> <sup>ΔHep</sup>) reduced the development of MASH and fibrosis in male mice.