ROC analysis showed that a model combining TyG-AIP with hypertension (AUC = 0.643) provided improved discrimination compared to hypertension alone (AUC = 0.571).<h4>Conclusions</h4>TyG-AIP is associated with increased stroke risk, particularly in dysglycemic individuals, and exhibits joint effects with hypertension. The gene discussed is AIP; the disease is Hypertension.