Immunological analysis demonstrated an elevated CD8<sup>+</sup> T cell proportion (<i>p</i> = 0.001), a decreased Treg cell proportion (<i>p</i> = 0.018), and a reduced CD4<sup>+</sup>/CD8<sup>+</sup> ratio (<i>p</i> = 0.019) in pediatric ITP patients. This evidence concerns the gene CD4 and autoimmune thrombocytopenic purpura.