Moreover, its precise cellular or molecular mechanisms in colitis remain unknown.<h4>Methods</h4>To evaluate the therapeutic potential of CU104, we tested CU104 in two colitis models: dinitrobenzene sulfonic acid (DNBS)-induced colitis in wild-type mice and dextran sodium sulfate (DSS)-challenged colitis in IL-10 knockout mice. This evidence concerns the gene IL10 and colitis.