Overexpression of ZBTB16 attenuated Ang II-induced inflammation, apoptosis, and migration and suppressed MMP-2/9 levels, indicating inhibited migratory activity.<h4>Conclusion</h4>We analyzed telomere-related signatures in AAA and identified two crucial biomarkers linked to the immune infiltration of patients. This evidence concerns the gene ZBTB16 and triple-A syndrome.